Archive for the ‘ Spirometry ’ Category




The objective of this video is to help guide respiratory professionals in the administration of the methacholine challenge test to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. This video is intended to enhance your knowledge and proficiency of the methacholine challenge test according to the American Thoracic Society and European Respiratory Society recommendations. It is a dose-response test; therefore the delivery of the methacholine and measurement of the response must be accurate in order to produce valid test results.



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Pediatric asthma lacks sensitive objective measures for asthma monitoring. The forced oscillation technique (FOT) offers strong feasibility across the paediatric age range but relationships between FOT parameter day-to-day variability and paediatric asthma severity and control are unknown.

Conclusions:  Increased day-to-day FOT variability exists in asthmatic school-aged children. Day-to-day Rrs variability was associated with asthma severity and with asthma control. FOT may be useful objective monitoring tool in paediatric asthma and warrants further study.


PubMed Central Canada (PMC Canada):

Within-Breath Analysis of Respiratory Mechanics in Asthmatic Patients by Forced Oscillation


?Forced oscillation technique (FOT): a new tool for epidemiology of occupational lung diseases?

G. P. Mishra1, T.M. Dhamgaye2, B.O. Tayade3, B. Fuladi Amol4, S. Agrawal Amit5, D. Mulani Jasmin6

1Department of Chest & TB, Government Medical College, Nagpur, India, 2Department of Chest & TB, BJ Medical College, Pune, India, 3Department of Chest & TB, NKP Salve Medical College, Nagpur, India, 4Dept. of Chest & TB, Government Medical College, Akola, India, 5Resident, Maimonides Medical Center, New York, USA, 6Rural Hospital, Rajegaon, Gondia, Maharashtra, India


Several prospective studies have found that impaired pulmonary function may increase the risk for developing

diabetes. [5] The pulmonary function in diabetics is characterized by restrictive lung defect. [6]

The interest in the relationship between diabetes and obstructive lung diseases has been pursued only recently. [1-4] The prevalence of asthma is significantly higher in patients with type II diabetes mellitus (DM), independent of other comorbid conditions. [1] Chronic obstructive pulmonary disease (COPD) may be a risk factor for developing NIDDM (Non In- sulin Dependent Diabetes Mellitus).

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The objective of this study was to better quantify the well-known ‚Äėproblem‚Äô of the change in interpretation of spirometry, as a consequence of the change from the other commonly used reference standards (Morris, Kory, Crapo, Knudson 1976, and¬†Knudson 1983) to NHANES III.



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American Journal of Respiratory and Critical Care Medicine


We analyzed the FEV1/FEV6 and FEV1/FVC results of 502¬†consecutive patients in the spirometric diagnosis of airway obstruction. We also examined the agreement between FEV6 and FVC in the spirometric diagnosis of restriction. Technically acceptable test results were obtained from 337¬†subjects (67%). The sensitivity of FEV1/FEV6 for diagnosing airway obstruction as defined by FEV1/ FVC was 95.0%; the specificity was 97.4%. When interpretations differed, the measured values were all close to the lower limits of the reference ranges. When analysis included ¬Ī¬†100-ml variability in FEV1 and FEV6, the sensitivity increased to 99.5% and the specificity to 100%. The reproducibility of FEV6 was superior to that of FVC. These results suggest that FEV6 is an accurate, reliable alternative to FVC for diagnosing airway obstruction and that FEV6 is reasonably comparable to FVC for the spirometric diagnosis of restriction. FEV6 is more reproducible and less physically demanding for patients.

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Asthma – COPD Spirometry Diagnosis Calculator

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Credit:National Research Institute of Tuberculosis and Lung Diseases

The detection of lung function disturbances has a great value

in health and disease. We use the lung function tests in the diag

nosis and monitoring procedures in different lung diseases and in

general medicine. These methods are also very useful in qualifica

tion of patients before thoracic surgery interventions, to deter

mine the grade of respiratory impairment in patients and in epide

miological studies evaluating the negative influences of outdoors

or indoors environment factors in workers and in inhabitants of

different regions.


Good resource for information on pulmonary function including:

Static & Dynamic

Lung Volumes
Lung Diffusing Capacity
Airways Resistance
Bronchial Provocation

Pulmonary Function

provoCheck it out HERE

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