Archive for the ‘ APRV ’ Category

Thank you to:
Babak Sarani, MD
Assistant Professor of Surgery
Co-Director of the Rapid Response Team
Division of Traumatology and Surgical Critical Care
University of Pennsylvania

Despite advances in ventilator management, 31% to 38% of patients with adult respiratory distress syn- drome (ARDS) will die, some from progressive respira- tory failure. Inability to adequately oxygenate patients with severe ARDS has prompted extensive efforts to identify what are now known as alternative modes of ventilation including high-frequency oscillatory venti- lation and airway pressure release ventilation. Both modalities are based on the principles of the open-lung concept and aim to improve oxygenation by keeping the lung uniformly inflated for an extended period of time.

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HFO_APRV published

APRV PowerPoint

David Pitts II, RRT


Clinical Applications Specialist, Maquet

Birmingham, Alabama

Sponsored by Maquet, Inc – Servo Ventilators

APRV (3.5 Mb)


APRV may be used safely in patients with ALI/ARDS, and decreases the need for paralysis and sedation as compared with PCV-inverse ratio ventilation (IRV). APRV increases cardiac performance, with decreased pressor use and decreased airway pressure, in patients with ALI/ARDS

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Current modes of ventilation explained:



    • Recruitable low compliance lung disorders
    • Lung dysfunction secondary to thoracic restriction i.e.. obesity, acites
    • Inadequate oxygenation with FiO2 > .60
    • PIP> 35 cmH2O and /or PEEP>10 cmH2O
    • Lung protective strategies (high PEEP, low Vt) are failing
  • Can be used with other interventions i.e.. INO therapy, prone positioning

  • APRV

    Airway Pressure Release Ventilation (Power Point)

    Ventilation Modes

    APRV Clinical Guide (From Respiratory Resource)

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