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FEV6 Is an Acceptable Surrogate for FVC in the Spirometric Diagnosis of Airway Obstruction and Restriction June 21, 2011

Posted by admin in : Featured Articles, Spirometry , comments closed

American Journal of Respiratory and Critical Care Medicine


We analyzed the FEV1/FEV6 and FEV1/FVC results of 502 consecutive patients in the spirometric diagnosis of airway obstruction. We also examined the agreement between FEV6 and FVC in the spirometric diagnosis of restriction. Technically acceptable test results were obtained from 337 subjects (67%). The sensitivity of FEV1/FEV6 for diagnosing airway obstruction as defined by FEV1/ FVC was 95.0%; the specificity was 97.4%. When interpretations differed, the measured values were all close to the lower limits of the reference ranges. When analysis included ± 100-ml variability in FEV1 and FEV6, the sensitivity increased to 99.5% and the specificity to 100%. The reproducibility of FEV6 was superior to that of FVC. These results suggest that FEV6 is an accurate, reliable alternative to FVC for diagnosing airway obstruction and that FEV6 is reasonably comparable to FVC for the spirometric diagnosis of restriction. FEV6 is more reproducible and less physically demanding for patients.

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APRV, PRVC, PAV September 19, 2010

Posted by admin in : APRV, Featured Articles, Multimedia Library, Strategies, Ventilation , comments closed

Current modes of ventilation explained:



    • Recruitable low compliance lung disorders
    • Lung dysfunction secondary to thoracic restriction i.e.. obesity, acites
    • Inadequate oxygenation with FiO2 > .60
    • PIP> 35 cmH2O and /or PEEP>10 cmH2O
    • Lung protective strategies (high PEEP, low Vt) are failing
  • Can be used with other interventions i.e.. INO therapy, prone positioning

  • APRV

    Airway Pressure Release Ventilation (Power Point)

    Ventilation Modes

    APRV Clinical Guide (From Respiratory Resource)

    High Tidal Volumes in Mechanically Ventilated Patients Increase Organ Dysfunction after Cardiac Surgery June 17, 2012

    Posted by admin in : Research/Studies/Education, Strategies, Ventilation , comments closed
    Tissue damage in lungs following high tidal volume mechanical ventilation Tissue sections of the lungs 

    In the multivariate analysis, high and traditional tidal volumes were independent risk factors for organ failure, multiple organ failure, and prolonged stay in the intensive care unit. Organ failures were associated with increased intensive care unit stay, hospital mortality, and long-term mortality.

    Conclusion: Tidal volumes of more than 10 ml/kg are risk factors for organ failure and prolonged intensive care unit stay after cardiac surgery. Women and obese patients are particularly at risk of being ventilated with injurious tidal volumes.

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    Asthma vs COPD online Calculator April 13, 2011

    Posted by admin in : Asthma, COPD, Quick Reference, Spirometry , comments closed


    Asthma – COPD Spirometry Diagnosis Calculator

    Enter FEV1/FVC  etc…

    Start the Application

    More CXR links, case studies, and examples. April 2, 2011

    Posted by admin in : CXR/Photos, CXR/Photos, Education/Studies , comments closed

    SRS-X The SRS Educational Resource

    Each Case of This Site is Supplied by the Members of KSTR.

    Virginia Commonwealth University – Pulmonary Case of the Week

    New Modes and New Concepts in Mechanical Ventilation (Prof Yehia Khater ) August 26, 2009

    Posted by admin in : Strategies, Ventilation , comments closed

    New Ventilation Modes

    •Dual Control

    Within-a-breath switches from PC to VC during the breath

    VAPS and pressure augmentation


    Pressure-Limited, Flow-Cycled Ventilation

    Volume support ventilation VSV Siemens 300

    Variable-pressure-support Cardiopulmonary

    corporation Venturi,

    Pressure-Limited, Time-Cycled Ventilation

    Pressure-regulated volume-control PRVC Siemens 300

    Adaptive pressure ventilation APV Hamilton Galileo

    Auto-flow Draeger Evita 4

    Volume-control Puritan Bennett 840

    Variable pressure control Cardiopulmonary

    corporation Venturi

    •Proportional-Assist Ventilation

    •Adaptive Support Ventilation

    •Automatic Tube Compensation

    •Airway Pressure-Release Ventilation

    Download Article in PDF form


    What Is Pleurisy? What Causes Pleurisy? July 26, 2009

    Posted by admin in : News, Quick Reference , comments closed



    Pleurisy, also known as pleuritis, is a condition that results from the swelling of the linings of the lungs and chest. The pleural cavity (area between lungs and inner chest wall) is created by two lubricated surfaces called pleura, the inner pleura lining the lungs and the outer lining the chest wall. A variety of factors can cause the pleura to become inflamed and rub against one another, rather than slide smoothly, as one breathes.

    What causes pleurisy?

    Pleurisy is a common complication of several different medical conditions, the most pervasive being a viral infection of the lower respiratory system.

    Other causes include:

    Bacterial infections such as pneumonia and tuberculosis

    A chest wound that punctured the pleural cavity

    A pleural tumor

    Autoimmune disorders like lupus and rheumatoid arthritis

    Sickle cell anemia


    Pulmonary embolism

    A heart surgery complication

    Lung cancer or lymphoma

    A fungal or parasitic infection

    Familial Mediterranean fever

    Infections can sometimes spread from person to person, but it is rare to “catch” pleurisy.

    SourcedFrom Sourced from: Respiratory / Asthma News From Medical News Today

    Infant Inhalation Of Ultrafine Air Pollution Linked To Adult Lung Disease: Shown For The First Time By LSUHSC July 25, 2009

    Posted by admin in : All Diseases, News, Research/Studies/Education , comments closed


    Stephania Cormier, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, has shown for the first time that early exposure to environmentally persistent free radicals (present in airborne ultrafine particulate matter) affects long-term lung function.

    SourcedFrom Sourced from: Respiratory / Asthma News From Medical News Today

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