Sepsis Package

September 20, 2008

Systemic Inflammatory Response Syndrome (SIRS)
The hallmark clinical manifestations of both sepsis and SIRS are two or more of the following conditions:
1. Temperature >38ºC or <36ºC (100.4/96.8) 2. Tachycardia >90 beats per minute
3. Respiratory rate >20 per minute or a PaCO2 <32 mm Hg 4. White blood cell count >12,000 mm3 or <4,000/mm3 or >10% immature (band) forms (“left shift”).
SSC Criteria

Infection plus any two, get lactate
Temp >101 or <96.5 Altered Mental Status Chills with Rigors Tachy>90
RR>20
WBC>12000 or <4000 Sugar>120 mg/dl in absence of diabetes

signs of severe sepsis, any of the following distinct from the source of infection
SBP<90 or MAP<65 or SBP decrease > 40 from baseline
Cr > 2.0 or UO < 0.5 cc/kg/hour Billi > 2 mg/dl
PLT < 100,000 Lactate >4
INR > 1.4 or PTT > 60
bilat infiltrates with criteria for ALI or need for increased supplemental O2 to maintain SpO2>90

XXsepsisEMCrit.org | Emergency Department Critical Care – Sepsis and Critical Care

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